Today there is a lot of talk of Low T in middle age men. With aging babyboomers there is a huge finacial market to market testosterone replacement in middle age to aging men.

However, the clinical importance of declining testosterone levels in older men is unclear. So what testosterone decline in aging men should be considered normal?

Male pattern baldness may be a telltale sign of heart disease, a review of six studies involving nearly 40,000 men suggests.

The meta-analysis, published in the online journal BMJ Open, showed that vertex baldness, but not frontal baldness, was significantly associated with an increased risk of chronic heart disease (CHD).

Lower testosterone levels were predictive of rheumatoid factor (RF)-negative rheumatoid arthritis (RA) in men according to a new case-control study. Low testosterone raised the odds for subsequent diagnosis of rheumatoid factor (RF)-negative RA by 69% as compared with men who had normal values. Men who developed RF-negative RA also had significantly higher levels of follicle-stimulating hormone prior to diagnosis.