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Apolipoprotein B May Better Predict the Risk of Heart Disease than LDL Cholesterol Levels

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Researchers believe that high blood levels of LDL particles lead to increased risk of narrowing of the arteries (atherosclerosis), coronary heart disease, and stroke.

A panel of diabetes and heart experts agreed that LDL (“bad”) cholesterol was still an important risk factor, but that after LDL cholesterol levels were brought under control, ApoB (a measure of the number of LDL particles in the blood that cause hardening of the arteries) should also be tested and treated to target levels in people at high risk.

The consensus statement emphasizes the need to examine all factors for heart disease, to continue to focus on lifestyle interventions to reduce the risk for type 2 diabetes and heart disease, and to more aggressively control all lipids.

The paper also urged health care providers to look at a person’s lifetime risk for heart disease, rather than just at short-term risks.

Last modified on Monday, 10 May 2010 18:18
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