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These Hormone Levels May Influence Weight Regain Featured

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The Hunger Hormone Connectionoprah_weight gain

The connection between appetite hunger hormones such as leptin and ghrelin and long-range weight-loss complications stems from work with 104 obese and overweight men and women, all of whom embarked on an eight-week, low-calorie diet.

Before dieting, during the diet, and about four months post-diet, the reserachers measured each participant's body weight and fasting plasma levels of leptin, ghrelin, and insulin.

The bottom-line: Those with higher leptin and lower ghrelin levels before dieting were more likely to reacquire the lost weight after the diet ended.
"We believe this research may indicate that the outcome of weight therapy may be pre-conditioned," according to study author Ana Crujeiras, of Complejo Hospitalario Universitario de Santiago in Spain in a news release from the Endocrine Society.

"Our findings may provide endocrinology and nutrition professionals a tool to identify individuals in need of specialized weight-loss programs that first target appetite hormone levels before beginning conventional dietary treatment," she added.

And while noting that "the long-term success of maintaining the weight lost is usually poor," Crujeiras suggested that the current observations "could be used as a tool to personalize weight-loss programs that could guarantee success in keeping off the weight."

SOURCE: Journal of Clinical Endocrinology & Metabolism, Sept. 9, 2010, news release.



Last modified on Sunday, 24 July 2011 16:03
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